2. Neurological Disease

Neurological Disease

Neurological Disease

Related Products

PDF 88.0 MB

A range of neurological disorders, including epilepsy and dystonia, may involve dysfunctional intracortical inhibition, and may respond to treatments that modify it. Parkinson’s is a neurodegenerative disease characterized by increased activity of GABA in basal ganglia and the loss of dopamine in nigrostriatum, associated with rigidity, resting tremor, gait with accelerating steps, and fixed inexpressive face. Neurological deficits, along with neuromuscular involvement, are characteristic of mitochondrial disease, and these symptoms can have a dramatic impact on patient quality of life. Neurological features may be manifold, ranging from neural deafness, ataxia, peripheral neuropathy, migraine, seizures, stroke‐like episodes and dementia and depend on the part of the nervous system affected.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P3593
    LPLRF-NH2 88280-21-1 98%
    LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons.
    LPLRF-NH2
  • HY-P3625
    Dynorphin (2-17), amide (porcine) 161874-98-2 98%
    Dynorphin (2-17), amide (porcine) is a dynorphin derivative with some analgesic effects. Dynorphin is a class of opioid peptides produced by the precursor protein dynorphinogen and is involved in pain, addiction and mood regulation.
    Dynorphin (2-17), amide (porcine)
  • HY-P3628
    Dynorphin (2-17) (porcine) 83608-80-4 98%
    Dynorphin (2-17) (porcine) is a peptide derived from Prodynorphin, can improve somatic signs of Morphine-dependent withdrawal.
    Dynorphin (2-17) (porcine)
  • HY-P3629
    Dynorphin B 29 (pig) 84376-30-7 98%
    Dynorphin B 29 (Leumorphin) (pig) is a petide. Dynorphin B 29 (pig) can interact with multiple receptors in the brain, as well as in isolated tissue systems. Dynorphin B 29 (pig) can be used for the research of immunoreaction.
    Dynorphin B 29 (pig)
  • HY-P3631
    SALMF amide 2 134439-74-0 98%
    SALMF amide 2, a neuropeptide S2 from the starfish Asterias rubens, is involved in the regulation of eversion of the cardiac stomach in starfish.
    SALMF amide 2
  • HY-P3632
    [DAla2, DArg6] Dynorphin A, (1-13) (porcine) 75921-88-9 98%
    [DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) is an opioid peptide (dynorphinl-13, DYN) derivative found in porcine pituitary extracts. DYN is highly potent at the peripheral opioid receptors GPI and MVD, but is readily and rapidly degraded in vivo. [DAla2, DArg6] Dynorphin A, (1-13) (porcine) has some resistance to enzymatic cleavage and prevents peptide cleavage by enzymes.
    [DAla2, DArg6] Dynorphin A, (1-13) (porcine)
  • HY-P3633
    Locustatachykinin II 126985-98-6 98%
    Locustatachykinin II (Lom-TK II) is an insect neuropeptide with homology to peptides of the vertebrate tachykinin family. Locustatachykinin II can be used for the research of insect endocrine.
    Locustatachykinin II
  • HY-P3634
    [DAla2] Dynorphin A (1-13), amide (porcine) 79985-43-6 98%
    [DAla2] Dynorphin A (1-13), amide (porcine) is a petide. [DAla2] Dynorphin A (1-13), amide (porcine) might have the κ opioid receptor agonist effect. [DAla2] Dynorphin A (1-13), amide (porcine) can be used for the research of nervous system.
    [DAla2] Dynorphin A (1-13), amide (porcine)
  • HY-P3635
    Cockroach Myoactive Peptide II 93240-39-2 98%
    Cockroach Myoactive Peptide II (Pea-CAH-II) is a cockroach neuropeptide. Cockroach Myoactive Peptide II is a member of the adipokinetic hormone/red pigment concentrating hormone (AKH/RPCH) family. Cockroach Myoactive Peptide II can be used for the research of metabolic functions of insect body.
    Cockroach Myoactive Peptide II
  • HY-P3636
    Cockroach Myoactive Peptide I 93208-51-6 98%
    Cockroach Myoactive Peptide I (Pea-CAH-I) is a cockroach neuropeptide, a member of the adipokinetic hormone/red pigment-concentrating hormone family (AKH/RPCH family).
    Cockroach Myoactive Peptide I
  • HY-P3641
    Kisspeptin 13 374675-18-0 98%
    Kisspeptin 13 inhibits glucose-induced insulin secretion with an IC50 of 1.2 nM. Kisspeptin 13 activates the hypothalamic-pituitary-adrenal (HPA) axis, causes hyperthermia, motor behavior and anxiety in rats. Kisspeptin 13 interacts with α2-adrenergic and 5-HT2 serotonin receptors, exhibits antidepressant efficacy. Kisspeptin 13 is an activator for GPR54 and GnRH receptor, which enhances memory and can be used in Alzheimer's disease research.
    Kisspeptin 13
  • HY-P3646
    [DAla2] Dynorphin A (1-9) (porcine) 95673-38-4 98%
    [DAla2] Dynorphin A (1-9) (porcine) is a dynorphin, which can be used in studies of analgesic, addiction, and depression.
    [DAla2] Dynorphin A (1-9) (porcine)
  • HY-P3647
    [DPro10] Dynorphin A (1-11), porcine 94596-26-6 98%
    [DPro10] Dynorphin A (1-11), porcine, a N-Alkylated derivative, is a potent κ-opioid receptor agonist with a Ki value of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine has analgesic property.
    [DPro10] Dynorphin A (1-11), porcine
  • HY-P3676
    Neuropeptide Y (3-36) (porcine) 143863-88-1 98%
    Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36.
    Neuropeptide Y (3-36) (porcine)
  • HY-P3677
    Neuropeptide Y (2-36) (porcine) 102961-52-4 98%
    Neuropeptide Y (2-36) (porcine) is a porcine-derived neuropeptide with 97.14% homology to rat/human origin. Neuropeptide Y (2-36) (porcine) is also a rat neuropeptide receptor agonist, with EC50 values of 1.2, 1.6 and 3.4 nM for receptor of Y5, Y2 and Y1 respectively. Neuropeptide Y (2-36) (porcine) can be used in studies related to obesity and eating disorders.
    Neuropeptide Y (2-36) (porcine)
  • HY-P3679
    Neuropeptide Y (1-24) (human) 131448-51-6 98%
    Neuropeptide Y (1-24) (human) is a neuropeptide with potencies in inhibiting the electricity stimulated twitch response of rat vas deferens. Neuropeptide Y (1-24) (human) stimulates N-methyl-D-aspartate (NMDA)-induced neuronal activation in the rat CA3 region of the dorsal hippocampus in vivo.
    Neuropeptide Y (1-24) (human)
  • HY-P3680
    [Nle13]-Motilin 55524-56-6 98%
    [Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist.
    [Nle13]-Motilin
  • HY-P3691
    CART (1-39), Human, Rat 98%
    CART (1-39), Human, Rat is a neuropeptide consisting of 1-39 residues of the CART peptide. CART (1-39), Human, Rat is a rat satiety factor with potent appetite-suppressing activity and is closely associated with leptin and neuropeptide Y. CART (1-39), Human, Rat inhibits both normal and starvation-induced feeding. CART (1-39), Human, Rat can induce anxiety and stress-related behavior.
    CART (1-39), Human, Rat
  • HY-P3692
    CART (55-76), rat 1815618-15-5 98%
    CART (55-76), rat is a neuropeptide (55-76 residues of the CART peptide) and constitutes the N-terminal fragments of CART (55-102). CART (55-76), rat is a rat satiety factor with potent appetite-suppressing activity and is closely associated with leptin and neuropeptide Y. CART (55-76), rat can induce anxiety and stress-related behavior.
    CART (55-76), rat
  • HY-P3712
    Cardioexcitatory peptide 1 127122-98-9 98%
    Cardioexcitatory peptide 1 is a cardioexcitatory neuropeptide, can be isolated from Achatina atria. Cardioexcitatory peptide 1 has potent cardio-excitatory action on the hearts and also modifies the motility of muscular tissues and neural activities.
    Cardioexcitatory peptide 1
Cat. No. Product Name / Synonyms Application Reactivity